News from the group:
Research Exchange Fellowships - IAESTE (apply)
CAMDA 2023 - ISMB Conference Track, 26-27 July, Lyon, France (read more)
World-leading patient stratification - graph based cancer data integration (read more)
Confirming molecular mechanisms of tendon regeneration - a powerful ovine fetal model (read more)
CAMDA 2022
ISMB Conference Track,
11-12 July, Madison, USA
(read more)
NVIDIA GTC Best Poster Award
for MM Kańduła
at GTC'18
Outstanding Presentation Prize
for MM Kańduła
at CAMDA'17
Outstanding Presentation Prize
for PP Łabaj
at CAMDA'15 (photo)
Austrian Marshall Plan Foundation scholarship
for MM Kańduła
at Boston University
OeAW APART fellowship
for PP Łabaj

Sequencing Quality Control (SEQC) project,
MAQC Consortium 2011–2014 (read more)
Host–parasite interactions in biocontrol, WWTF grant 2010–2013 (read more)

Power and limitations of RNA-Seq,
FDA SEQC, Nature Biotechnology (read more)
Characterization and improvement of RNA-Seq precision,
Bioinformatics (read more)
Impact of heavy tails in microarray analysis, Bioinformatics (read more)
Novel conserved repeats in sorting signals,
FEBS Journal (read more)
Sound sensation gene,
Nature communications
(read more)
RNA interference in ageing research,
Gerontology (read more)

Bioinformatics Research at the Institute for Molecular Biotechnology

We are interested in the study of complex systems in living organisms. Novel views augmenting the classical gene by gene approaches are required to overcome the engineered redundancies and combinatorial effects prevalent in higher eukaryotes. We therefore combine

  • work to establish improved quantitative experimental assays, such as RNA-Seq, microarrays, or differential in-gel electrophoresis, and
  • the development of modern computational methods, such as hierarchical probabilistic models or the integration of heterogeneous data sources,

focussed by biological studies in our laboratory and collaborations.

Highlights of our research include:

  • Optimization of microarray design, probe signal interpretation (read more)
  • Advanced models and tools for expression profiling (read more)
  • State-of-the-art applications and integrated analyses (read more)

Originally the Vienna Science Chair of Bioinformatics, the research group was founded 2005 on winning a five-year WWTF startup grant together with its partners. It then became a permanent chair embedded in the Dept of Biotechnology and was endowed by Boku University Vienna until 2013. It now forms an independent Research Group at the newly founded Institute for Molecular Biotechnology.

Vienna Skyline